Decreased CD10-positive granulocytes for the differential diagnosis of myelodysplastic syndrome

Myelodysplastic syndromes (MDS) are highly heterogeneous myeloid neoplasms, and a large number of patients are difficult to diagnose and classify by blood and bone marrow examination. As a surface marker of granulocyte, studies have shown CD10 can be used to define the degree of granulocyte maturation in MDS patients. However, whether it can be used for differential diagnosis of MDS and other hematological diseases remains inconclusive. To explore the value of CD10 for differential diagnosis of MDS, 60 newly diagnosed MDS, 20 aplastic anemia (AA) patients, and 35 iron-deficient anemia (IDA) patients were selected for this study. Bone marrow (BM) specimens were processed for surface marker analysis and labeled with pre-conjugated monoclonal antibodies. Stained cells were detected by flow cytometry. Our results indicated that CD10-positive granulocytes were significantly decreased in BM of MDS patients than AA and IDA patients, and the level of CD10-positive mature granulocytes was not associated with the clinical stages of malignancy. Receiver operating characteristic (ROC) areas under the curve (AUC) of CD10-positive granulocytes was 0.86 and 0.85, respectively, in MDS patients than the IDA group and AA group with good specificity and sensitivity. Further, CD10-positive granulocytes were increased after effective treatment. In conclusion, we found the decrease in CD10-positive granulocytes has a differential diagnostic value of MDS.     

外墙保温系统中粘结材料的检测技术分析

选择了几份典型的外墙外保温系统标准,通过对这几份标准中胶粘剂和抹面胶浆的成型和检测方法的比较,分析了现有检测技术的优劣,并结合工作实践提出了建议。     

New exact solutions of the Tzitzéica-type equations in non-linear optics using the expa function method

One specific class of non-linear evolution equations, known as the Tzitzéica-type equations, has received great attention from a group of researchers involved in non-linear science. In this article, new exact solutions of the Tzitzéica-type equations arising in non-linear optics, including the Tzitzéica, Dodd–Bullough–Mikhailov and Tzitzéica–Dodd–Bullough equations, are obtained using the exp_a function method. The integration technique actually suggests a useful and reliable method to extract new exact solutions of a wide range of non-linear evolution equations.     

A Voltage Control Method for a Distributed Line Feeder by means of Multiagent Approach

This paper proposes a method for the coordinated control of power factor by means of a multiagent approach. The proposed multiagent system consists of two types of agent: single feeder agent (F_AG) and bus agent (B_AG). In the proposed system, an F_AG plays as an important role, which decides the power factors of all distributed generators by executing the load flow calculations repeatedly. The voltage control strategies are implemented as the class definition of Java into the system. In order to verify the performance of the proposed method, it has been applied to a typical distribution model system. The simulation results show that the system is able to control very violent fluctuation of the demands and the photovoltaic (PV) generations.     

基于现场监测与数值模拟的浅层采空区稳定性分析

隐患采空区是目前影响露天开采矿山安全生产的主要危害源之一。随着台阶开采的不断剥离,露天开采境界内各台阶与地下空区群的隔离层厚度越来越薄,随时有可能发生采空区顶板坍塌事故。考虑到露天矿采空区地质赋存条件和围岩稳固性等特征,以弓长岭露天铁矿浅层采空区为工程背景,运用现场监测和数值模拟相结合的手段综合分析了浅层采空区的稳定性。将液体静力水准地表沉降监测系统的监测数据与FLAC数值模拟结果对比,调整蠕变参数使得数值模拟的蠕变速率与现场监测结果一致,而后据此进行未来结果的预测。最终根据地表沉降数据确定的蠕变参数取值为A=1.0×10^-12、m=1.75、n=0.35。研究表明:静力水准测点地表最大沉降位移为-9.8 mm,蠕变计算结果顶板最大垂直位移约20.4 mm,应力最大值约25 MPa,综合分析显示该采空区较稳定。上述研究提供了一种基于采空区现场监测数据的数值模拟蠕变分析方法,可为类似矿山采空区稳定性分析提供借鉴。     

Maximum likelihood-based adaptive differential evolution identification algorithm for multivariable systems in the state-space form

Parameter estimation plays an important role in the field of system control. This article is concerned with the parameter estimation methods for multivariable systems in the state-space form. For the sake of solving the identification complexity caused by a large number of parameters in multivariable systems, we decompose the original multivariable system into some subsystems containing fewer parameters and study identification algorithms to estimate the parameters of each subsystem. By taking the maximum likelihood criterion function as the fitness function of the differential evolution algorithm, we present a maximum likelihood-based differential evolution (ML-DE) algorithm for parameter estimation. To improve the parameter estimation accuracy, we introduce the adaptive mutation factor and the adaptive crossover factor into the ML-DE algorithm and propose a maximum likelihood-based adaptive differential evolution algorithm. The simulation study indicates the efficiency of the proposed algorithms.     

河南渑池地区铝土矿工艺矿物学及锂的赋存状态研究

通过河南省渑池地区含锂铝土矿(岩)层工艺矿物学分析,查明铝土矿的物质组成、嵌布特征、伴生锂分布特征和赋存状态,为矿产综合利用提供理论依据。结果显示:该铝土矿Al2O3含量为54.8%,铝硅比值(A/S)为2.6,铝土矿层和粘土岩层中Li2O含量均高于伴生锂边界品位,粘土岩中锂更为富集；矿物组成除一水硬铝石之外,主要是以集合体形态产出的粘土矿物。采用稀酸解析、选矿测试和电子探针分析锂的赋存状态,查明矿石中锂主要是以类质同象置换形式赋存在伊利石和高岭石等粘土矿物中；选矿富锂尾矿中Li2O可富集到0.57%左右,是锂综合回收利用的重点研究对象。      

斗轮取料机液压控制系统的故障分析及改进

针对臂式斗轮取料机运行中抖动现象,进行了故障分析和排除,并对其液压原理和元件选型进行了优化及改进,为相关液压系统的故障分析和设计选型提供参考。     

Passive micromixer with baffles distributed on both sides of microchannels based on the Koch fractal principle

Since the beginning of the 21st Century, the development of microfluidic chip technology has been very rapid and has attracted the attention of more and more scholars. As an important part of the microfluidic chip, the performance of the micromixer is critical. The fractal structure in the microchannels helps to improve the mixing performance of the micromixer and improve the mixing efficiency of the micromixer. The research results of other scholars are of great significance to the research of the present paper, which mainly studies the effect of changing the baffle state on the mixing efficiency of the micromixer based on the Koch fractal principle. Through simulation analysis, it was found that the mixing efficiency of the baffles distributed on both sides of the microchannel was higher than the mixing efficiency of the baffles distributed on the microchannel side. When the distance between adjacent baffles was divided into 0.15, 0.25 and 0.35 mm, simulated data suggested that the baffle distance of 0.15 mm was best. Increasing the number of baffles from six to eight groups increased the mixing path of the fluid in the microchannel and improved mixing efficiency. A comparison of mixing efficiencies of the 0°, 15° and 30° baffle angles revealed that very significant improvement in mixing efficiency was obtained at 30°. © 2019 Society of Chemical Industry